For Health Care Providers

Reporting MIS-C

Health care providers should report suspected cases of Multisystem Inflammatory Syndrome In Children (MIS-C) to KDHE within 4 hours of suspicion. Complete the Kansas Reportable Disease Form (PDF) then return as follows:

  • Send via secure email to the Epi Hotline OR fax to 877-427-7318 
  • AND call the KDHE Epidemiology Hotline at 877-427-7317
  1. Diagnosing
  2. Testing
  3. Treating
  4. Coding
  5. Resources

Diagnosing MIS-C 

The public health surveillance case definition for MIS-C is: 

  • An individual aged <21 years presenting with fever*, lab evidence of inflammation**, and evidence of clinically severe illness requiring hospitalization, with multisystem (≥2) organ involvement (cardiac, renal, respiratory, hematologic, gastrointestinal, dermatologic or neurological); AND

  • No alternative plausible diagnoses; AND

  • Positive for current or recent SARS-CoV-2 infection by RT-PCR, serology, or antigen test; or exposure to a suspected or confirmed COVID-19 case within the 4 weeks prior to the onset of symptoms

*Fever ≥38.0ᵒC for ≥24 hours, or report of subjective fever lasting ≥24 hours

** Including, but not limited to, one or more of the following: an elevated C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), fibrinogen, procalcitonin, d-dimer, ferritin, lactic acid dehydrogenase (LDH), or interleukin 6 (IL-6), elevated neutrophils, reduced lymphocytes and low albumin